This symposium shines a spotlight on groundbreaking initiatives and programs that expand access to HIV prevention and treatment care while empowering patients with agency and choice. It showcases policies and regulations that shape health systems and impact patient experiences, emphasizing those that foster an environment conducive to patient-centered care. A diverse international panelist discussion will amplify non-traditional and culturally appropriate approaches to HIV care that break down barriers, integrate with other healthcare services, and offer replicable models for adoption in different contexts. Join us to explore these innovative solutions that drive positive change in HIV prevention and treatment care on our journey towards zero new HIV infections and improved quality of life for individuals with HIV.