Carlos Chivardy Moreno

The session shows cost-effectiveness of long-acting injectable pre-exposure prophylaxis (PrEP) for adolescent girls and young women (AGYW) in South Africa, differentiated service delivery in Mozambique, the Advance HIV Care Package in Malawi, and the predicted HIV infection rates for cabotegravir in Brazil.

The studies shed valuable insights on HIV prevention and treatment strategies. Anne Neilan underscores the significance of potentially cost-effective pricing for long-acting injectable PrEP (CAB-LA) as an alternative for adolescent girls and young women (AGYW) in South Africa, effectively addressing challenges related to daily PrEP (tenofovir, TDF/FTC-based) adherence. Dorlin Moiana Uetela's research showcases economic advantages of implementing differentiated service delivery (DSD) models in Mozambique. Using modeling and decision tree analysis, her findings demonstrate improved client retention and cost savings for the health system, thereby reinforcing the imperative for continued implementation of DSD models. Emily Hyle's comprehensive study, employing the CEPAC model, focuses on the Advanced HIV Care Package (AHD) in Malawi. It demonstrates cost-effectiveness of the package in comparison to other strategies, emphasizing its potential to enhance clinical outcomes and advocating for its global incorporation into HIV care programs. Furthermore, Andrew Hill's investigation delves into the projected HIV infection rates for cabotegravir in Brazil; it highlights the importance of using compulsory licenses to enhance access to new drugs at affordable prices. These important findings contribute to our understanding of economic aspects of HIV control strategies, underscoring the crucial need for cost-effective and context-specific approaches to effectively combat the HIV epidemic.

The session presents diverse HIV prevention and treatment studies, offering valuable insights. Critical analysis ensures effective translation of findings. A holistic approach optimizes the impact of interventions in the global fight against HIV. Important contributions to HIV control strategies emerge from the session. However, potential limitations and contextual factors affecting generalizability must be considered. Economic analysis methods and assumptions always warrant scrutiny, necessitating additional sensitivity analyses and robustness tests. Implementing strategies face challenges in different settings, requiring further assessment for scalability. Successful implementation demands a comprehensive approach involving multi-stakeholder collaboration, policy adaptation, and context consideration.