HIV prevention is a driving force for ending AIDS as a public health problem by 2030. As part of combination HIV prevention, VMMC is a proven-effective prevention intervention. To date, VMMC has been predominantly delivered through vertical service delivery approaches, with implementing partners supporting national programs to scale up to higher coverage focusing on adolescents and adult men. Embedding biomedical HIV prevention and VMMC services within overall health systems aligns with global efforts to strengthen health systems and achieve universal health coverage. In this session we will share results from research and implementation towards more sustainable biomedical HIV prevention programming and financing in priority countries in Eastern and Southern Africa.